วันจันทร์ที่ 28 พฤศจิกายน พ.ศ. 2554

Georgia Tech designs new software for drug development - Pharmaceutical Business Review

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Science Codex


Georgia Tech designs new software for drug development

Pharmaceutical Business Review


The new Symmetry-adapted perturbation theory (SAPT) helps gain further insights into interactions between molecules including those between a drug and its target, rdmag.com reported. The computer program generated by Georgia Tech Professor of Chemistry ...


Georgia Tech develops software designed to improve drug development

R & D Magazine



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วันศุกร์ที่ 25 พฤศจิกายน พ.ศ. 2554

Obama Leaves God out of Thanksgiving Speech, Riles Critics - ABC News

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ABC News


Obama Leaves God out of Thanksgiving Speech, Riles Critics

ABC News


The popular website of London's Daily Mail has taken the issue global, with a story under the headline "What a Turkey! Outrage as Obama Leaves God Out of His Thanksgiving Address." PHOTO : President Barack Obama and daughter Sasha.


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วันพุธที่ 23 พฤศจิกายน พ.ศ. 2554

Former Metro leader boards Cincinnati streetcar effort with proposal - Business Courier of Cincinnati:

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Michael Setzer, who left Metrop last March to become regionap vice presidentfor Chicago-based , is listed as the lead contac t person for . It’s one of four groups that responderd to a city of Cincinnati reques forstreetcar proposals. “I’m encouraged that we have that kind of saidMichael Moore, interim director of the city’sw department of transportation and engineering. “kI hope it means that we’ves got some good alternatives for a A city consultant estimatee a rail system linking the riverfront to Uptow n neighborhoods surrounding the woulsdcost $185 million.
City Manager Miltonm Dohoney has pegged it at upto $219 City officials have identified $67 million in funding sources. Last they placed streetcars on a listof “ready to projects assembled by the . It is lobbyingv President Obama to spend heavily on infrastructurein cities. Cincinnati estimatee a $132 million federal contribution to the streetcar systemm would lead to the creation of150 jobs. It was one of four dozeh projects in which the cityrequested $435 million for roads, water works and economic development It predicted the 48 pro­jects wouldf create 4,012 jobs. City leaders also askerd streetcar vendors to describe how they would cover upto $91 millioh in financing costs.
Four submitted proposals: Setzer’s company; ; of St. Mo.; and of Bensalem, Pa. Amony Veolia’s partners are , , , , and with . Setzed declined to comment pending a city interview process, but a competitor considers him a frontrunner. “We’dr consider the Veolia group our primary in part becauseof Mike’s experience locally,” said Dave senior project engineer in URS’s downtownb office.

วันจันทร์ที่ 21 พฤศจิกายน พ.ศ. 2554

FDA gives OK to Avastin in brain cancer - Silicon Valley / San Jose Business Journal:

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Accelerated approval is provisional, based on preliminary evidencer suggesting a drug is beneficialagainst life-threatening Avastin’s effectiveness is based on an improvement in objective responsre rate, Genentech said, but there is no data from randomized controlleds trials demonstrating an improvement in disease-relatedd symptoms or increased survival. A course of treatmenr reportedly costsabout $40,000. A global Phase III tria l using Avastin in patients with newly diagnosedx glioblastoma will beginenrollment soon, Genentechu said. Glioblastoma affects about 10,000 people per year including Sen.
Ted Kennedy — and more than 90 percen t of patients see tumors return following treatment with chemotherapyand “Today’s approval would not have been possible without the dedication of physicians, patient advocates, the FDA and, most importantly, the people who participaterd in the clinical trials and their familiess who had the couragse to support them,” said Dr. Hal Genentech’s executive vice president of globall development and chiefmedical officer. Avastin, whichb registered U.S. sales of $2.
7 billion last year, last month faileds a late-stage trial with post-surgical colon cancer The drug, approved for types of colon, lung and breast cancer, was central to negotiationsz during ’s successful $47 billion takeoverr of South San Francisco-based because new uses for Avastin could increase its salesa by billionsof dollars. Avastin works by blocking vascular endothelialgrowth factor, or VEGF, a protein that helps develop and maintaij blood vessels, including those that feed tumors.

วันเสาร์ที่ 19 พฤศจิกายน พ.ศ. 2554

What's next for Manny? - Philippine Star

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Bleacher Report


What's next for Manny?

Philippine Star


Manny Pacquiao is blessed by Fr. Marlon Beof with Freddie Roach, Buboy Fernandez and fighter Dennis Laurente at Mass in the Mandalay Bay Theater the morning of the fight before over 1000 fans. It wasn't the best of fights for WBO welterweight champion ...


Manny Pacquia o: 7 Reasons He Should Retire After Beating Juan Manuel Marquez

Bleacher Report


Handwrappper Rafael Garcia: Manny Pacquiao cannot beat my man, Floyd Mayweather

Examiner.com


Was Manny Pacquiao's Hair a Factor in the Fight?

FightSaga


EastsideBoxing.com -ESPN -BoxingScene.com


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วันพฤหัสบดีที่ 17 พฤศจิกายน พ.ศ. 2554

Financial firm helping clients deal with stress from downturn - The Business Journal of Milwaukee:

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“We were all strugglingf with what the market wastelling us,” said who is a certified financial planner and presiden t of , a fee-only firm in “I just saw a lot of peoplw with a high level of The first thing he did was hold two workshops in collaborationh with a family money The workshops drew a total of about 30 peopl and provided advice for clientz such as making sure they had cash reserves and maintainedd their credit rating as well as they could. The family moneyu therapist discussed coping mechanisms for the anxiety people felt about financialo matters and participants also shared thei r own stressmanagement techniques.
The firm also steppe d up its communicationwith clients, making sure all were contactee at least once every 10 business days. In the past, Haubrich said clientws usually were contacted at least every 20 or30 days. It seemedx to bear results, Haubrich said. “During the tax preparation season, we just had a lot of peoples show up with a high degree of peace of which told me that high level of communicatiohn and touch really helped them an awful he said.
After he gained more clarity about what was happeningb with the economy and stock Haubrich put together another workshopl for clients about personal The firm has held four of the which can accommodate12 people, and will offed one more in June. The firm will continue to hold the workshop until demandfalls off. The 90-minute session includes an overview of the economy andstockj market, but also discusses dimensions of personakl sustainability, including health, relationship, career and “We didn’t look at this as a marketing he said. “We looked at makingv sure we were serving the needs ofour clients, giving them strategiess and tactics to deal with this economicv reset.
” But as a side the firm is seeing an influx of new clients and Dick Outland and Frances Bedford attended one of Haubrich’ personal sustainability workshops in April. Outland and a Racine married couple, are both retired and longtimd clients. They said they were concerned about the hit theie retirement income has but also find Haubrich to be agood “What I got out of it mostly was the comfortg that he has a lot of knowledgse in this area and that the man that we entrust to manages our resources knows what he’s doing,” Outland said.
Bedford also said it’s comfortinh when you’ve given so much responsibility to an adviser that heknowsw what’s happening in the market and how it’s affectingf his clients and will provide good Haubrich provided “a reinforced confidence that all is well even thoughb things are not well,” she Financial Service Group also has a virtua client center that has a client’s complete including tax returns and estate plannin g documents online through a securse server. The firm invested in the tool a coupled of years agoand that’s paying off now, Haubrichy said.
Revenue is down like it is for everyone infinancial planning, he said, but demand for service is up. Haubrich already offers a service to his clients calledx CareerAsset Management, which integrates financial planningh services with career Now he’s working with career coacyh Jane Schroeder to developp a more intensive workshop specifically on career sustainability.

วันอังคารที่ 15 พฤศจิกายน พ.ศ. 2554

Rite-Hite leaving Memphis for Horn Lake, Miss. - Business First of Buffalo:

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The Milwaukee, Wis.-based company, which manufactures loading dock safet systems and industrialdoor products, is moving operations from its 130,000-square-foot Outlandc Road facility to 200,000 square feet in , an industriaol park in Horn Lake. Louide Patron, vice president of manufacturingb for theMemphis Rite-Hite facility, said the company will move its 65 currentt employees to Horn Lake. “At peak capacity, we have 130 but we have 40 to 50 that have been laid Patron said.
“When the economy improves, they’lkl get the first chance to come Patron said the company is moving its operations to consolidate some productds it had subcontractedmanufacturing for, but also to prepare for new productse the company is planning to build out of the new facility. The Memphisd location currently manufacturesdock levelers, which are the steell bridges that cover gaps in storage docks and tractor trailers. Rite-Hite has had an operationsw in Memphissince 2002. Patroj said the Mississippi move will be completedeby Nov. 1. Scott Pahlow, executive vice presidenty at Grubb & Ellisw Co., brokered the leasd for Rite-Hite.

วันอาทิตย์ที่ 13 พฤศจิกายน พ.ศ. 2554

วันพฤหัสบดีที่ 10 พฤศจิกายน พ.ศ. 2554

More Californians able to afford homes - Los Angeles Times

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Los Angeles Times


More Californians able to afford homes

Los Angeles Times


The real estate group calculated the monthly payment for a mortgage on such a home to be $1540, including taxes and insurance, and assuming a 20% down payment and a 4.63% interest rate. More Californians able to afford homes.



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วันอังคารที่ 8 พฤศจิกายน พ.ศ. 2554

GSK collaborating on drive for advanced skin cancer drug - Triangle Business Journal:

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Synta (NASDAQ:SNTA) of Lexington, Mass., will receivre an upfront cash paymentof $80 It will be eligible to receive milestone paymentes of up to $135 million if the drug is approved, up to $450 millionj if it is approved for othef diseases and up to $300 million in salee milestone payments. GlaxoSmithKline could purchase upto $45 million of Synta'ws common stock depending on undisclosed The new drug candidate developed by Synta, STA-4783, is entering phase-III clinical trials -- typically the last step before submitting a new drug applicatiohn with the Food and Drug Administration.
The companies will sharse responsibility for development and commercializatio nof STA-4783 in the Uniteed States, while GlaxoSmithKline will have exclusives responsibility for development and commercialization of the melanomaw treatment outside of the country. Melanoma is the deadliest skin cancer. Its incidence has grown more than other cancers over the past accordingto GlaxoSmithKline. About 60,000 American s will be diagnosed with melanoma this year andaboutg 8,200 will die from the Metastatic melanoma is an advanced Based in London, GlaxoSmithKlin (NYSE:GSK) has its U.S. headquartersx in Philadelphia.

วันอาทิตย์ที่ 6 พฤศจิกายน พ.ศ. 2554

Bolivian MPs Condemn US Plot against Iran - Fars News Agency

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Press TV


Bolivian MPs Condemn US Plot against Iran

Fars News Agency


In response, Iran's top security official Saeed Jalili on Friday released a number of documents detailing US involvement in acts of terror against the Islamic Republic. Secretary of Iran's Supreme National Security Council (SNSC) Saeed Jalili made the ...


Iran Nat ional Day anti-US protests gets wide coverage

Islamic Republic News Agency


'US planning anti-Iran acts of sabotage'

Press TV



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วันศุกร์ที่ 4 พฤศจิกายน พ.ศ. 2554

Greater Washington Initiative: Region

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percent this year for the firs t time in more than20 years, accordin to the Greater Washington Initiative. The the research and marketing affiliate ofthe , made the projectionn in its 2009 Regionak Report, released Wednesday morning at the . The reporty says the region’s GRP — the total values of its economy including goods and services hit $454 billion in up 2 percent. That makes it the fourth-largest regional econom in the nation, the group said, following New Los Angeles and Chicago. The group defines the region more broadly than thefederapl government’s metropolitan statistical area. The initiative’sa definition is D.C.
; Montgomery, Prince George’s, Howard, Anne Arundel, Calvert, Charle and St. Mary’s counties in Maryland; and Alexandri and Arlington, Fairfax, Loudoun, Prince William, Fauquier, Stafforxd and Spotsylvania counties in The projected drop in GRP is because the region has postedr positive annual growth even in pastnationalk recessions. But the area’se top economist disagrees withthe projection. Stephen Fuller, director of the Center for Regional Analysisat , predict slight growth — 1.2 percen t — in 2009 and graduak growth to 3.2 percent in 3.7 in 2011 and 4.2 in 2012.
Fuller said the discrepancu between his number and the GreatedrWashington Initiative’s has to do with the countiese included in the study. Fuller spoke at the report’s unveiling and assistefd with the report but was not responsible for itsfinal version. Though his numbers differ from the Fuller said theGRP hasn’t grown this slowlt since the early 1990s, when it crawled at 0.2 percent a Still, chanting the ever-popular “wse have the federal government” mantra, the GWI maintainzs that the D.C. area will bounce back fastetr than othermetropolitan areas. Matt Erskine, executive director of the GWI, citedx the economic stimulus, Washington’s $65.
4 billion in federao procurement — nearly $20 billion over the closest California — and the area’xs “global connectivity” as reasons for a faster recessio nrecovery time. But with everyg recession comes unemployment andthe D.C. area is no exception. Fullert predicts a mere 13,500 growthh in jobs this year, less than the 1 percent in growthg needed to absorb college and high schoola grads entering thework force. “People know the markef is traditionally betterin D.C., so that adds extra Fuller said. “Hopefully they go Fuller predicts unemployment will peakmid year-2010. “It takeds until about September to absorb the new work he said.
“Especially with companies hiring for seasona positionsor part-time work.” Fuller said the Washington area will maintaihn its current structure with more than 20 percent of jobs in the professionapl and business services nearly 12 percent in the federal governmen t and 11 percent in education and The initiative’s report said the region’s biggest job secto continued to be professional services in with nearly 23 percent of the jobs in that category. Secondc was the federal government, with 11.6 percent, followeds by education and health, 11.2 percent; statde and local government, 10.4 retail, 8.8 percent; and hospitality and 8.7 percent.

วันพุธที่ 2 พฤศจิกายน พ.ศ. 2554

Jury awards Centocor $1.7B in patent case against Abbott - St. Louis Business Journal:

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An Abbott spokesman said the companywill Horsham, Pa.-based Centocor, a divisiob of (NYSE:JNJ), makes the blockbuster rheumatoisd arthritis treatment Remicade, and had sued Abbotf over Abbott’s arthritis drug, Humira. Both are so-called anti-TNd arthritis treatments. Horsham, Pa.-based Centocor said it is the exclusive licensese ofthe patent, which is co-ownec by . Centocor President Kim Taylor said “thwe jury recognized our valuablwintellectual property, finding our patent both valid and We will continue to assert intellectual propertu rights for our immunology as they offer significant advances in treatmentr for patients with a number of immun e mediated inflammatory diseases.
” Abbott spokesman Scotyt E. Stoffel said, “We are disappointedc in this verdict, and we are confidengt in the merits of our case and that we will prevailpon appeal. “The evidence clearly established that Humira was the first ofits fully-human anti-TNF antibody medicine,” Stoffel said. “JNJ’ss anti-TNF antibody medication, Remicade, is partially made from mouse DNA. JNJ did not launch a fully-humahn product until April 2009. In fact, only when Humirsa was nearing its approvalk in 2002 did JNJ amend the patent at issuew in this litigation to claim that it haddiscovered fully-human antibodie s in 1994.
JNJ acknowledged at trial that it did not start working ona fully-human antibody until 1997 two years after Abbott discovered Humira and one year afte Abbott filed its patent applicationzs for Humira.”